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Erstwhile group of researchers "A" ran an RCT. The placebo group ate & drank normally. The intervention group was given 167ml/day of DHMO (RDI/12) in addition to their normal food and drink. The trial lasted for 4 years.
RESULTS: There was no statistical difference between the placebo and the intervention group.
CONCLUSION: In this trial, DHMO made no difference to the subjects well-being, weight, body-fat percentage or anything else, apart from a statistically-significant increase in urinary volume. DHMO is therefore ineffective and long-term use may result in kidney damage.
Erstwhile group of researchers "B" ran an RCT. The placebo group ate & drank normally. The intervention group was given 60,000ml once a month of DHMO (RDI x 30) in addition to their normal food and drink. The trial was intended to last for 3 months, but was terminated after 1 month.
RESULTS: There was 100% mortality in the intervention group, compared to the placebo group.
CONCLUSION: In this trial, the RDI of DHMO killed 100% of the subjects. DHMO is therefore toxic.
Daily Mail Headline: Studies prove that DHMO kills! Parliament calls for an immediate ban.
DHMO is water (H2O).
The reason why I wrote the above spoof is because that's how Vitamin D3 is often tested in RCTs. Either daily "homoeopathic", or infrequent "standing on the sun" doses are used. Result? Failure. Therefore, Vitamin D is deemed to be either ineffective or toxic. See also Why randomized controlled trials of calcium and vitamin D sometimes fail.
The RDI for Vitamin D3 is 400iu/day, ~1/12 of what I take (5,000iu/day). Blood test results for 25(OH)D and Corrected Ca are in the RR (25(OH)D is near the top end and Corrected Ca is near the bottom end).