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| From http://grannychoe.com/recipe3_Soup.php |
In Ultra-high-fat (~80%) diets: Fat storage, and a delicious analogy, I analogised the effect of carbohydrate consumption on mean serum glucose level with the effect of fat consumption on mean serum triglyceride level. Here's another one.
Chronic excessive consumption of carbohydrates relative to what are being burned results in excessive fat synthesis in the liver, resulting in excessively-high fasting serum triglyceride level, which is harmful.
Chronic excessive consumption of fats relative to what are being burned results in excessive cholesterol synthesis in the liver, resulting in excessively-high fasting VLDL, LDL & IDL level, which is harmful.
Seems legit.
4 comments:
It's probably true to say that no-one needs shit they don't need. Encouraging inefficiencies in metabolism by oversupplying substrates of any type when storage mechanisms are downregulated is unlikely to be an optimal behaviour except perhaps in the short-term as a form of training.
And, face it, for many people expanding or contracting body fat stores are one way they learn to judge energy balance. Humans are the only animal with a mirror. If someone becomes more or less immune to this effect, they may miss a cue they've become dependent on.
In a recent series of comments on Hyperlipid, Nige said [to Peter D]: "I like to have dietary flexibility. This includes ~100g/d of low-GI carbs."
Nige--may I ask how how you manage to get to ~100g/d if the carbs are all low-GI? Or perhaps I should first ask how you define "low-GI." I recall you previously preferring the categories of fast vs slow carbs. Low-GI/slow carbs certainly means something different to, say, Dr Bernstein (who counts the carbs in an egg! [0.36g] vs Jennie-Brand Miller (who defines Low-GI as 55 or less [where glucose=100]--which thereby permits her to include long-grain white rice and white spaghetti in the Low-GI category!]
But without some smallish portions of, say, rice or cooked-and-cooled potatoes, would it not require a rather unpalatably hefty quantity of broccoli & string beans & salad-stuff to reach ~100g/d?
As I don't measure what I eat, I could be in error. I eat:-
~300g/day of broccoli (~4% carbs).
~200g/day of mixed veg (~7% carbs).
~25mL/day sweet chilli & other sauces (~30% carbs).
~100g/day various beans (~25% carbs).
~125mL/day Gold Top milk (~7% carbs).
~10g/day sugar.
~375mL/day fruit juices (~10% carbs).
~750mL/day low-sugar fizzy drinks (~5% carbs).
That's ~152g/day. It's amazing how much a few carbs here & there adds up to.
PPTGs are also created by intestinal cells, which have similar lipid-synthetic functions to hepatocytes and adipocytes: http://atvb.ahajournals.org/content/33/5/1056.long
Is there such a thing as fatty gut disease?
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