Monday, 4 August 2014

Historical perspectives on the impact of n-3 and n-6 nutrients on health, by Bill Lands.

Here's Fig. 1. from http://www.sciencedirect.com/science/article/pii/S0163782714000253
Relating tissue HUFA balance with blood cholesterol and heart attacks. Results from the 25-year follow-up in the Seven Countries Study [35] were discussed in an earlier review [10] which noted that “Food energy imbalances which elevate blood cholesterol may be fatal only to the degree that omega-6 (n-6) exceeds omega-3 (n-3) in tissue HUFA. Such evidence raises questions about the hypothesis that blood cholesterol levels cause CHD.” Northern Europe and Southern Europe have abbreviations “No.” and “So.”, respectively. The Figure is reprinted with permission of the publisher.

Hat-tip to Dr. Thomas Dayspring for Tweeting this review.

Fig. 1 is interesting, as it shows a significant association between 25-year CHD mortality and Serum Total Cholesterol for every region except Japan. What's different about Japan, compared to Northern Europe, USA, Serbia, Southern Europe & Crete?

According to Measuring Blood Fatty Acids as a Surrogate Indicator for Coronary Heart Disease Risk in Population Studies , Philippines & Iceland have lower % linoleic acid than Japan. Where's the CHD vs TC data?

Could another difference be that the Japanese eat rice, a relatively intact grain, instead of foods made from wheat grain dust (i.e. flour) as their main source of dietary carbohydrates?

See also Using 3–6 differences in essential fatty acids rather than 3/6 ratios gives useful food balance scores , and Omega 3-6 Balance Score.

16 comments:

charles grashow said...

http://suppversity.blogspot.com/2014/08/rice-original-bodybuilding-supplement.html

http://www.icmr.nic.in/ijmr/2014/june/0610.pdf
Effects of gamma oryzanol supplementation on anthropometric measurements & muscular strength in healthy males following chronic resistance training

http://www.fastlearners.org/Bill%27s%20Papers/2009Arithmetic.pdf
Measuring Blood Fatty Acids as a Surrogate Indicator for Coronary Heart Disease Risk in Population Studies

http://www.nutritionandmetabolism.com/content/9/1/46
Using 3–6 differences in essential fatty acids rather than 3/6 ratios gives useful food balance scores

http://www.fastlearner.org/Omega3-6Balance.htm
Omega 3minus6 Balance Score

charles grashow said...

http://nigeepoo.blogspot.com/2014/08/historical-perspectives-on-impact-of-n.html

Nigel Kinbrum said...

Recursive: See Recursive.

Nigel Kinbrum said...

"http://suppversity.blogspot.co.uk/2014/08/rice-original-bodybuilding-supplement.html "
See http://www.webmd.com/vitamins-supplements/ingredientmono-770-gamma%20oryzanol.aspx?activeingredientid=770
"Gamma oryzanol is a substance that is taken out of rice bran oil."
∴ It's only in brown rice. It's not in white rice. :-(

"http://www.fastlearners.org/Bill%27s%20Papers/2009Arithmetic.pdf
Measuring Blood Fatty Acids as a Surrogate Indicator for Coronary Heart Disease Risk in Population Studies"
Nice find. There's dietary data for Philippines & Iceland, but no CHD vs TC data. :-/

"http://www.nutritionandmetabolism.com/content/9/1/46
Using 3–6 differences in essential fatty acids rather than 3/6 ratios gives useful food balance scores"
Nice find.

"http://www.fastlearner.org/Omega3-6Balance.htm
Omega 3minus6 Balance Score"
Nice find.

I'll add the last two links to the post.

weilasmith said...

Hi, Nigel. When that person you talked to me about thought you had Asperger's, what exactly was it about you that made him/her feel that way? Just curious.

Nigel Kinbrum said...

I think it was a combination of me rattling off obscure facts about Diet & Nutrition at high speed, and me being completely oblivious to people's body language.

I have no idea if I'm boring someone, or annoying someone etc. That's probably why Wooo has regular melt-downs at me, as I don't recognise the imminent signs of a melt-down, when I'm annoying her by being picky about facts.

weilasmith said...

but you don't really mind her melt-downs, right? you just want to engage in discussion and have mental stimulation. am i correct? if so, you might need to use your scientific mind to look for patterns in woo's behavior to see what makes her not want to engage you in the way you would like. that enterprise might be interesting in and of itself. first of all, don't say or imply any outright rude stuff, like the sister thing. if you like drama, you can continue that kind of comment. but if you want to engage with someone technical and practical knowledge about diet like wooo, it might pay off to look for ways to be better received.

Nigel Kinbrum said...

"but you don't really mind her melt-downs, right?"
Correct. I've been called far worse things than what Woo calls me! Sticks & stones...

"you just want to engage in discussion and have mental stimulation. am i correct?"
Ooh, yeah!

"if so, you might need to use your scientific mind to look for patterns
in woo's behavior to see what makes her not want to engage you in the
way you would like."
I'm not sure if that would work. There seems to be a random element to Woo's posts. The one about carnivory & fasting was excellent, and I left a comment accordingly, which Woo liked!

The one after that seemed to revert to an old and incorrect way of thinking, with the use of vague terms, and no definition for the word "Obesity".

Obesity is officially defined as:- BMI >30
BMI is a function of body weight & height.

Body weight is determined by the balance between Ein & Eout, over a period of time.

∴ Obesity is determined by the balance between Ein & Eout, over a period of time, i.e. CICO. Q.E.D.

I think that Woo has defined obesity in her own mind as "excessive fat mass", which explains her writings. She's still wrong. Her insistence that she's right and that anybody who disagrees with her is an idiot, to be dismissed with a hand-wave, annoys me. She does this regularly.

I don't like the "echo-chamber" Comments section on her blog, where all of her "yes-people" congratulate her on every post, no matter how wrong it is.

My initial response to her was scathing, as I was annoyed at her hypocrisy and her downright lies about me. That comment is still there, but I've edited-out the nastiness.

In conclusion, I think that I'm probably wasting my time posting there.

weilasmith said...

most commenters are just people with experiences gaining and losing weight, like me. most don't have strong science backgrounds, again like me.


anyway, if you still enjoy posting and you aren't blocked, might as well keep posting.


if you can't feel someone's annoyance, then you should get somewhat of a pass, in my opinion, if you are annoying to them. it's like i'm not going to rag on someone's poor taste in colors if they are color blind or their poor singing voice if they are tone deaf. i just let that go and engage with the person in an area where they don't have a deficit. i think woo has many instances of distorted thinking, but occasionally i try to engage her in areas i am interested in, even though she can be extremely rude. if i learn something interesting and/or helpful, then i win. if i get a rude response, it's about the same as dealing with a rude cashier. i don't need to see or talk to them.

Nigel Kinbrum said...

"most commenters are just people with experiences gaining and losing weight, like me. most don't have strong science backgrounds, again like me."
I like to help people, which is why I answered your query.

"anyway, if you still enjoy posting and you aren't blocked, might as well keep posting."
I'll probably "pass through" every now and again, just see what horrors are being committed ;-).

If I keep a low profile, Woo seems to be happy. I did go a bit "comment-crazy", but there were so many unanswered comments, somebody had to do it! :-D

"if you can't feel someone's annoyance, then you should get somewhat of a pass, in my opinion, if you are annoying to them."
I disagree. It's my responsibility to make myself less annoying to others. I will try to show a little more sensitivity - unless it's a troll - in which case I'll tell them to **** off!

I won't bull-shit someone. If I believe that they're wrong, I'll tell them - and why - in great detail! I did it to Gary Taubes & Richard Feinman Ph.D, and I'll do it to anyone, no matter how high-ranking or important they are.

weilasmith said...

thanks for trying to help me. i appreciate it.

StellaBarbone said...

As an engineer turned physician and a member of an engineering family, I would be inclined to diagnose you as an engineer. CICO via Weight Watchers worked brilliantly for me since it was all about measuring and recording. I love to put things in numbers. I loved patients who were engineers because I could explain things as negative feedback loops and the like with perfect comprehension.

Nigel Kinbrum said...

Yay for engineers!

I love to find out how things work, so that I can explain it to someone else in a way that they can understand.

Are you still working as a physician?

StellaBarbone said...

I retired last year. I miss (some of) the people, but not the work or the commute.

Nigel Kinbrum said...

You're welcome.

I've noticed that quite a few of my comments are disappearing shortly after appearing, so it looks as though Woo has set some restricted words that result in my comments being rejected. I'm not going to comment there any more.

Nigel Kinbrum said...

As you're a retired physician, you must know a lot of physician-y things.

If you spot any errors in what I've written, please comment. My last error-checking slave died! ;-) :-D